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1

“Chemical Mutation” by Amino Acid Exchange in the Reactive Site of a Proteinase Inhibitor and Alteration or Its Inhibitor Specifity

Dr. Herbert R. Wenzel, Prof. Dr. Harold Tschesche

Journal:

Angewandte Chemie International Edition

Year:

1981

Language:

english

File:

PDF, 264 KB

english, 1981

2

Dysfunction of dysferlin-deficient hearts

Katrin Wenzel, Christian Geier, Fatimunnisa Qadri, Norbert Hubner, Herbert Schulz, Bettina Erdmann, Volkmar Gross, David Bauer, Ralf Dechend, Rainer Dietz, Karl Josef Osterziel, Simone Spuler, Cemil Ö

Journal:

Journal of Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 561 KB

english, 2007

3

4.4.2 Lessons Learned from Synchronizing Complex Systems Development within Automotive Industry

Negele, Herbert, Schmidt, Reinhard, Finkel, Stephan, Wenzel, Stefan

Journal:

INCOSE International Symposium

Year:

2006

Language:

english

File:

PDF, 1.14 MB

english, 2006

4

4 Customer in the Loop (CIL) - The Product Development Cycle Model-

Wenzel, Stefan, Negele, Herbert

Journal:

INCOSE International Symposium

Year:

1999

Language:

english

File:

PDF, 636 KB

english, 1999

5

Concurrent Engineering and more… A Systematic Approach to Successful Product Development

Wenzel, Stefan, Bauch, Thomas, Fricke, Ernst, Negele, Herbert

Journal:

INCOSE International Symposium

Year:

1997

Language:

english

File:

PDF, 562 KB

english, 1997

6

9.2.3 Successful Implementation and Application of Continuous Risk Management to Complex Systems Development in the Automotive Industry

Negele, Herbert, Pfletschinger, Thilo, Wenzel, Stefan, Getto, Gerhard

Journal:

INCOSE International Symposium

Year:

2005

Language:

english

File:

PDF, 423 KB

english, 2005

7

6.1.2 Determining the Impact of Change within your Method- and Toolbox for System Development

Wenzel, Stefan, Igenbergs, Eduard, Negele, Herbert

Journal:

INCOSE International Symposium

Year:

2001

Language:

english

File:

PDF, 690 KB

english, 2001

8

„Chemische Mutation” durch Aminosäureaustausch im reaktiven Zentrum eines Proteinase-Inhibitors und Ånderung seiner Hemmspezifität

Dr. Herbert R. Wenzel, Prof. Dr. Harald Tschesche

Journal:

Angewandte Chemie

Year:

1981

Language:

german

File:

PDF, 249 KB

german, 1981

9

Die Bedeutung der Rigidität des Peptidrückgrats für die Inhibitoreigenschaften des BPTI – gezeigt mit semisynthetischen Strukturvarianten

Christian Groeger, Dr. Herbert R. Wenzel, Prof. Dr. Harald Tschesche

Journal:

Angewandte Chemie

Year:

1993

File:

PDF, 389 KB

1993

10

Komplexe Biosynthese in Myxobakterien: Bildung der Leupyrrine in Sorangiumcellulosum

Helge Björn Bode, Silke C. Wenzel, Herbert Irschik, Gerhard Höfle, Rolf Müller

Journal:

Angewandte Chemie

Year:

2004

Language:

german

File:

PDF, 207 KB

german, 2004

11

The Importance of the Rigidity of the Peptide Backbone for the Inhibitory Properties of BPTI Demonstrated by Semisynthetic Structural Variants

Dipl.-Chem. Christian Groeger, Dr. Herbert R. Wenzel, Prof. Dr. Harald Tschesche

Journal:

Angewandte Chemie International Edition

Year:

1993

Language:

english

File:

PDF, 391 KB

english, 1993

12

Unusual Biosynthesis of Leupyrrins in the Myxobacterium Sorangium cellulosum

Helge Björn Bode, Silke C. Wenzel, Herbert Irschik, Gerhard Höfle, Rolf Müller

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

13

Synthese eines bifunktionellen Spin-Labels zur Quervernetzung von Proteinen

Herbert R. Wenzel, Gabriele Becker, Eberhard von Goldammer

Journal:

European Journal of Inorganic Chemistry

Year:

1978

File:

PDF, 113 KB

1978

14

ChemInform Abstract: Novel Heterocyclic Inhibitors of Matrix Metalloproteinases: Three 6H-1,3,4-thiadiazines

Joerg Schroeder, Herbert Wenzel, Hans-Georg Stammler, Anja Stammler, Beate Neumann, Harald Tschesche

Journal:

Year:

2001

File:

PDF, 28 KB

2001

15

Berechnung von binären Verdampfungsgleichgewichten mit Hilfe der Zustandsgleichung nach Redlich und Kwong

Prof. Dr. Siegfried Peter, Dr. Herbert Wenzel

Journal:

Chemie Ingenieur Technik

Year:

1971

Language:

german

File:

PDF, 311 KB

german, 1971

16

Berechnung von binären Phasengleichgewichten mit einer überkritischen Komponente

Dr. Herbert Wenzel, Prof. Dr. Siegfried Peter

Journal:

Chemie Ingenieur Technik

Year:

1971

Language:

german

File:

PDF, 644 KB

german, 1971

17

Zur Berechnung chemischer Gasgleichgewichte bei hohen Drücken

Prof. Dr. Siegfried Peter, Dr. Herbert Wenzel

Journal:

Chemie Ingenieur Technik

Year:

1973

Language:

german

File:

PDF, 438 KB

german, 1973

18

Die selektive Hydrierung von Acetylen im Herstellungsverfahren für Vinylchlorid

Dipl.-Ing. Herbert Müller, Dr. Klaus Deller, Dr. Gerhard Vollheim, Wenzel Kühn

Journal:

Chemie Ingenieur Technik

Year:

1987

Language:

german

File:

PDF, 389 KB

german, 1987

19

Notiz über Synthese und biochemische Eigenschaften eines Spin-Label-Nicotinamid-adenin-dinucleotids

Wolfgang E. Trommer, Herbert Wenzel, Gerhard Pjeiderer

Journal:

European Journal of Organic Chemistry

Year:

1974

File:

PDF, 186 KB

1974

20

Purification of the biologically active copolymers of maleic anhydride by supercritical fluid extraction

Andrzej B. Jarz¸bski, Andrzej I. Lachowski, Jolanta Maślińska-Solich, Herbert Wenzel

Journal:

Macromolecular Rapid Communications

Year:

1990

Language:

english

File:

PDF, 201 KB

english, 1990

21

Phase equilibrium by equation of state: a short-cut method allowing for association

Herbert Wenzel, Eugeniusz Krop

Journal:

Fluid Phase Equilibria

Year:

1990

Language:

english

File:

PDF, 1.49 MB

english, 1990

22

Strong crossreaction of human anti-aprotinin antibodies from heart transplant patient with [Arg15] aprotinin

Thomas Brinkmann, Reiner Körfer, Herbert R. Wenzel, Harald Tschesche, Knut Kleesiek

Journal:

Immunopharmacology

Year:

1997

Language:

english

File:

PDF, 647 KB

english, 1997

23

Negative differential conductance in a benzene-molecular device

Maarten R. Wegewijs, Matthias Hettler, Wolfgang Wenzel, Herbert Schoeller

Journal:

Physica E: Low-dimensional Systems and Nanostructures

Year:

2003

Language:

english

File:

PDF, 127 KB

english, 2003

24

Über Cyanmelamin und Cyanammelin (Ein Beitrag zur Aufklärung des Reaktionsmechanismus der Melamin-Bildung aus Dicyandiamid)

Herbert Bieling, Manfred Radüchel, Gerhard Wenzel, Hans Beyer

Journal:

Advanced Synthesis & Catalysis

Year:

1965

Language:

german

File:

PDF, 848 KB

german, 1965

25

Über Cyanmelamin und Cyanammelin (Ein Beitrag zur Aufklärung des Reaktionsmechanismus der Melamin-Bildung aus Dicyandiamid)

Herbert Bieling, Manfred Radüchel, Gerhard Wenzel, Hans Beyer

Journal:

Advanced Synthesis & Catalysis

Year:

1965

Language:

german

File:

PDF, 848 KB

german, 1965

26

Enzymatic semisynthesis of aprotinin homologues mutated in P′ positions

Christian Groeger, Herbert R. Wenzel, Harald Tschesche

Journal:

The Protein Journal

Year:

1991

Language:

english

File:

PDF, 580 KB

english, 1991

27

Chemical semisynthesis of aprotinin homologues and derivatives mutated inp′positions

Christian Groeger, Herbert R. Wenzel, Harald Tschesche

Journal:

The Protein Journal

Year:

1991

Language:

english

File:

PDF, 562 KB

english, 1991

28

ThepH dependence of the equilibrium constantKHydfor the hydrolysis of the Lys15-Ala16reactive-site peptide bond in bovine pancreatic trypsin inhibitor (aprotinin)

Jürgen Siekmann, Herbert R. Wenzel, Eduard Matuszak, Eberhard von Goldammer, Harald Tschesche

Journal:

The Protein Journal

Year:

1988

Language:

english

File:

PDF, 394 KB

english, 1988

29

Semisynthesis of Arg15, Glu15, Met15, and Nle15-aprotinin involving enzymatic peptide bond resynthesis

Jürgen Beckmann, Armin Mehlich, Werner Schröder, Herbert R. Wenzel, Harald Tschesche

Journal:

The Protein Journal

Year:

1989

Language:

english

File:

PDF, 693 KB

english, 1989

30

Semisynthetic engineering of proteinase inhibitor homologues

Harald Tschesche, Jürgen Beckmann, Armin Mehlich, Eugen Schnabel, Ernst Truscheit, Herbert R. Wenzel

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1987

Language:

english

File:

PDF, 329 KB

english, 1987

31

Aprotinin derivatives with chromophoric leaving groups can be used as highly selective active-site titrants for serine proteinases and permit the determination of kinetic constants of enzyme-inhibitor complexes

Armin Mehlich, Jürgen Beckmann, Herbert R. Wenzel, Harald Tschesche

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1988

Language:

english

File:

PDF, 1.17 MB

english, 1988

32

Semisynthetic aprotinin derivatives with specific alterations at the reactive-site peptide bond can be used to study structure-function relationships

Armin Mehlich, Jürgen Beckmann, Herbert R. Wenzel, Harald Tschesche

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1989

Language:

english

File:

PDF, 1.06 MB

english, 1989

33

BPTI backbone variants and implications for inhibitory activity

CHRISTIAN GROEGER, HERBERT R. WENZEL, HARALD TSCHESCHE

Journal:

Chemical Biology & Drug Design

Year:

1994

Language:

english

File:

PDF, 698 KB

english, 1994

34

Spin-Labelled AMP –an Activator of Phosphorylase

Stephen J. W. BUSBY, Marcus A. HEMMINGA, George K. RADDA, Wolfgang E. TROMMER, Herbert WENZEL

Journal:

Year:

1976

Language:

english

File:

PDF, 492 KB

english, 1976

35

Binding Studies of a Spin-Labelled Oxidized Coenzyme to Bovine-Liver Glutamate Dehydrogenase

Alt ZANTEMA, Wolfgang E. TROMMER, Herbert WENZEL, George T. ROBILLARD

Journal:

Year:

1977

Language:

english

File:

PDF, 864 KB

english, 1977

36

The refined 2.2-Å (0.22-nm) X-ray crystal structure of the ternary complex formed by bovine trypsinogen, valine-valine and the Arg15 analogue of bovine pancreatic trypsin inhibitor

Wolfram BODE, Jochen WALTER, Robert HUBER, Herbert R. WENZEL, Harald TSCHESCHE

Journal:

Year:

1984

Language:

english

File:

PDF, 660 KB

english, 1984

37

Preparation of chemically ‘mutated’ aprotinin homologues by semisynthesis : P1 substitutions change inhibitory specificity

Jürgen BECKMANN, Armin MEHLICH, Werner SCHRÖDER, Herbert R. WENZEL, Harald TSCHESCHE

Journal:

Year:

1988

Language:

english

File:

PDF, 816 KB

english, 1988

38

Structure-Based Design and Synthesis of Potent Matrix Metalloproteinase Inhibitors Derived from a 6H-1,3,4-Thiadiazine Scaffold

Schröder, Jörg, Henke, Andreas, Wenzel, Herbert, Brandstetter, Hans, Stammler, Hans G., Stammler, Anja, Pfeiffer, Wolf D., Tschesche, Harald

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 344 KB

english, 2001

39

Dimer-to-tetramer transformation: loop excision dramatically alters structure and stability of the ROP four α-helix bundle protein

Michael W Lassalle, Hans-Jürgen Hinz, Herbert Wenzel, Metaxia Vlassi, Michael Kokkinidis, Giovanni Cesareni

Journal:

Journal of Molecular Biology

Year:

1998

Language:

english

File:

PDF, 596 KB

english, 1998

40

The synthesis of spin-label derivatives of NAD+ and its structural components and their binding to lactate dehydrogenase

Herbert R. Wenzel, Gerhard Pfleiderer, Wolfgang E. Trommer, Klaus Paschenda, Albrecht Redhardt

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1976

Language:

english

File:

PDF, 604 KB

english, 1976

41

The nature of the substrate inhibition in lactate dehydrogenases as studied by a spin-labeled derivative of NAD+

Wolfgang E. Trommer, Helga Huth, Herbert R. Wenzel

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1979

Language:

english

File:

PDF, 802 KB

english, 1979

42

Ternary complex formation of pig heart lactate dehydrogenase with spin-labelled coenzymes and inhibitors as studied by electron spin resonance

Herbert R. Wenzel, Wolfgang E. Trommer

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1979

Language:

english

File:

PDF, 517 KB

english, 1979

43

Hydroxamate derivatives of substrate-analogous peptides containing aminomalonic acid are potent inhibitors of matrix metalloproteinases

Dirk Krumme, Herbert Wenzel, Harald Tschesche

Journal:

Year:

1998

Language:

english

File:

PDF, 105 KB

english, 1998

44

The Leupyrrins: A Structurally Unique Family of Secondary Metabolites from the Myxobacterium Sorangium c ellulosum #

Bode, Helge Björn, Irschik, Herbert, Wenzel, Silke C., Reichenbach, Hans, Müller, Rolf, Höfle, Gerhard

Journal:

Journal of Natural Products

Year:

2003

Language:

english

File:

PDF, 85 KB

english, 2003

45

The ‘oddball CNV’ as an indicator of different information processing in patients with panic disorders

Christian Korunka, Thomas Wenzel, Herbert Bauer

Journal:

International Journal of Psychophysiology

Year:

1993

Language:

english

File:

PDF, 744 KB

english, 1993

46

The Formula of Concord: Quadricentennial Essays || Legitimate Limits of Doctrinal Pluralism According to the Formula of Concord

Wenzel Lohff and Herbert J. Bouman

Journal:

Sixteenth Century Journal

Year:

1977

Language:

english

File:

PDF, 334 KB

english, 1977

47

Stability studies on derivatives of the bovine pancreatic trypsin inhibitor

Schwarz, Herbert, Hinz, Hans Juergen, Mehlich, Armin, Tschesche, Harald, Wenzel, Herbert R.

Journal:

Year:

1987

Language:

english

File:

PDF, 891 KB

english, 1987

48

Stereochemical Determination and Complex Biosynthetic Assembly of Etnangien, a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangium cellulosum

Menche, Dirk, Arikan, Fatih, Perlova, Olena, Horstmann, Nicole, Ahlbrecht, Wiebke, Wenzel, Silke C., Jansen, Rolf, Irschik, Herbert, Müller, Rolf

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 1.74 MB

english, 2008

49

Designable electron transport features in one-dimensional arrays of metallic nanoparticles: Monte Carlo study of the relation between shape and transport

Semrau, Stefan, Schoeller, Herbert, Wenzel, Wolfgang

Journal:

Physical Review B

Year:

2005

Language:

english

File:

PDF, 519 KB

english, 2005

50

A Textbook of Entomology

Wenzel, R. L., Ross, Herbert H.

Journal:

Year:

1949

Language:

english

File:

PDF, 807 KB

english, 1949

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